• Report: anthrax antibiotic should be stockpiled locally

    A new report describes a plan for the United States to be better prepared in the event of a bioterrorist attack using anthrax; the report recommends that public health officials in high-risk areas should consider stockpile anthrax antibiotics in local locations to make it easier to dispense quickly to an area of need, rather than continuing to use the single national stockpile

  • Real-time disease monitoring can help improve diagnoses

    Discovering epidemics or knowing when one is brewing is particularly difficult at the local level as doctors lack a broader perspective of what is occurring; to help provide local doctors with better information that could help stem the spread of infectious diseases, public health officials are pushing for the creation of a real-time national disease monitoring system

  • Japanese attenuated smallpox vaccine shows promise in U.S. trial

    An attenuated smallpox vaccine that was developed in Japan in the 1970s compared well with a conventional smallpox vaccine in a phase 1-2 clinical trial in the United States

  • Mapping the spread of drug-resistant influenza

    The movie “Contagion” is not based on real events, but it is not science fiction, either: certain strains of influenza are becoming resistant to common treatments; a team of researchers map out how this phenomenon is happening globally

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  • Budget cuts could hurt biodefense efforts

    With lawmakers struggling to reduce spending and cut the deficit, funding for government programs aimed at thwarting biological threats could face severe budget cuts; while the budget for overall civilian biodefense increased by 17 percent, that number is deceiving as federal agencies consolidated and combined several key programs under larger budget line item headings

  • Biological weapons: U.S. must not repeat the failure of imagination

    Joel McCleary, a biological weapons expert, is the chairman and co-founder of Q Global and the founder of PharmAthene; he argues that the U.S. government has not done enough to protect the nation against a biological attack, warns of the need for presidential leadership, and underscores the dangers of biological weapons

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  • Scientists "domesticate" -- and disarm -- malaria parasite

    Malaria is one of the Earth’s most notorious scourges, accounting for more than 250 million new cases — and one million deaths — each year, researchers have developed a novel technique to “tame” the malaria parasite by forcing it to depend on an external supply of a vital chemical; this could help to speed up drug development and provide the basis for the first effective vaccine against malaria

  • Lawmakers struggling to end critical medicine shortage

    Critical shortages for medicines needed in treating life-threatening illnesses have lawmakers and public health officials scrambling to find solutions; this year alone, a record high of more than 180 drugs crucial for treating childhood leukemia, breast and colon cancer, infections, and other diseases have been declared in short supply

  • Overcoming dangerous antibiotic-resistant bacteria

    Scientists have successfully reengineered an important antibiotic to kill the deadliest antibiotic-resistant bacteria; the compound could one day be used clinically to treat patients with life-threatening and highly resistant bacterial infections

  • Coriander oil tackles food poisoning and drug-resistant infections

    Coriander oil has been shown to be toxic to a broad range of harmful bacteria; its use in foods and in clinical agents could prevent food-borne illnesses and even treat antibiotic-resistant infections, according to the authors of a study published in the Journal of Medical Microbiology

  • How did H1N1 become an pandemic?

    The last century has seen two major pandemics caused by the H1N1 virus — the Spanish Flu in 1918 and 2009’s Swine Flu scare, which had thousands travelling with surgical masks and clamoring for vaccination; scientists, however, did not know what distinguished the Swine Flu from ordinary influenza in pigs or seasonal outbreaks in humans, giving it the power to travel extensively and infect large populations; until now

  • Medical silver bullet: New drug cures most viral infections

    Researchers at MIT’s Lincoln Lab have developed technology that may someday cure the common cold, influenza, and other ailments; the researchers tested their drug against fifteen viruses, and found it was effective against all of them — including rhinoviruses that cause the common cold, H1N1 influenza, a stomach virus, a polio virus, dengue fever, and several other types of hemorrhagic fever

  • Gold nanoparticles help to diagnose flu in minutes

    Arriving at a rapid and accurate diagnosis is critical during flu outbreaks, but until now, physicians and public health officials have had to choose between a highly accurate yet time-consuming test or a rapid but error-prone test; University of Georgia researchers offer a solution

  • Transforming acids into bases

    Chemists at the University of California, Riverside have accomplished in the lab what until now was considered impossible: transform a family of compounds which are acids into bases; the research offers vast family of new catalysts for use in drug discovery, biotechnology

  • Anthrax vaccine program demonstrates 36 month product stability

    Maryland-based PharmAthene has achieved an important program milestone in its recombinant protective antigen (rPA) anthrax vaccine program, and demonstrated thirty-six month stability of its rPA drug product candidate; the data suggest that the rPA product candidate is both highly stable and potent; stability has historically been a stumbling block for other recombinant anthrax vaccine programs